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Inflammation of vessels inflammatory process causes damage to the vessel wall and fibrinoid necrosis lumen becomes narrow or total occlusion happens due to thrombosis -causing tissue ischaemia and necrosis clinical manifestation depends on (a) size of the vessel involved for e,g small , medium and large (b) one or many organs involved ( c ) site of involvement


  1. Santos Bacchiega AB, Gomes Ochtrop ML, de Souza AWS. Systemic vasculitis. In: Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors. Autoimmunity: From Bench to Bedside [Internet]. Bogota (Colombia): El Rosario University Press; 2013 Jul 18. Chapter 36. Available from:
  2. Jatwani S, Goyal A. Vasculitis. [Updated 2021 Aug 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from:


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