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Acute kidney injury : detection

Presented here is a concise table outlining NICE's key recommendations on detecting Acute Kidney Injury for accurate clinical assessments."

CriteriaDetailsExplanation
(p)RIFLE, AKIN, KDIGO definitionsUsed for categorizing severityDifferent systems/definitions for acute kidney injury.
Serum creatinine rise ⬆️26 micromol/litre or greater within 48 hoursRapid decline in kidney function.
Serum creatinine increase ⬆️50% or greater rise within the past 7 daysIndicator of decreased kidney function.
Urine output fall for adults ⬇️Less than 0.5 ml/kg/hour for more than 6 hoursReduced urine output is a symptom of kidney injury.
Urine output fall for children and young people ⬇️Less than 0.5 ml/kg/hour for more than 8 hoursThe time frame varies between adults and children.
eGFR fall in children & young people ⬇️25% or greater fall within the past 7 daysA decrease in eGFR is a sign of kidney injury in children & young people.

Reference: Recommendations | Acute kidney injury: prevention, detection and management | Guidance | NICE


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