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The National Institute for Health and Care Excellence (NICE) provides comprehensive guidance for the management of adrenal insufficiency, a potentially life-threatening condition characterized by insufficient production of adrenal hormones. This guidance is essential for ensuring timely identification, appropriate referral, and effective management of patients with suspected adrenal insufficiency.
In this overview, we will focus on the key aspects of Section 1.2: Initial Identification and Referral, Section Management during physiological stress and criteria for When to Suspect Adrenal Crisis. These sections offer critical insights into recognizing the signs and symptoms of adrenal insufficiency, the pharmacological interventions recommended for ongoing management, and the urgent identification and treatment of adrenal crisis, a severe and potentially fatal complication.
Condition or Symptom | Consideration for Adrenal Insufficiency |
---|---|
Unexplained Hyperpigmentation | A key sign, though it may not be visible on black or brown skin—ask about skin color changes and assess buccal mucosa or scars. |
Persistent Symptoms/Signs: | - Weight loss: Potential glucocorticoid or mineralocorticoid deficiency. |
- Salt craving: Indicates potential aldosterone deficiency. | |
- Nausea or vomiting: Common symptoms of cortisol deficiency. | |
- Lack of appetite or unable to eat a full meal: Could be related to adrenal insufficiency affecting metabolism. | |
- Diarrhoea... |
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