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Benign skin tumors : differentials

This table lists the clinical characteristics of commonly seen benign skin tumours in primary care for quick reference.


Tumor TypeClinical FeaturesCommon Sites
Seborrheic KeratosisWaxy, "pasted-on" appearance, brown-to-blackFace, chest, back
DermatofibromaFirm, brown nodules, dimple signLegs
LipomaSoft, mobile, subcutaneous noduleTrunk, extremities
HemangiomaBright red birthmark, rubbery bumpAnywhere
Cherry AngiomaSmall, bright red papulesTrunk
Epidermoid CystSmooth, mobile cysts under the skinTrunk, neck, face
NeurofibromaSoft, fleshy, skin-coloured or slightly darker nodulesVarious
Pyogenic GranulomaSmall, reddish bump that bleeds easilyHands, arms
KeloidOvergrown scar, darker than surrounding skinAny scar site
Digital Myxoid CystSmooth, skin-colored bumps, commonly near nail bedsDigits
Acrochordon (Skin Tag)Small, soft, skin-coloured growthsEyelids, neck, armpits
KeratoacanthomaDome-shaped, keratin-filled growth, may resemble SCCSun-exposed areas

Reference: Luba MC, Bangs SA, Mohler AM, Stulberg DL. Common benign skin tumors. Am Fam Physician. 2003 Feb 15;67(4):729-38. PMID: 12613727.




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