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Bias and confounding

Bias and confounding

Bias and confounding are critical concepts in medical statistics and research, as they can significantly influence the validity of study results. Understanding these concepts is vital for clinicians, researchers, and medical students, as it helps in critically appraising the medical literature and conducting robust research.


Bias refers to any systematic error in the design, conduct, or analysis of a study that results in a mistaken estimate of an exposure's effect on the risk of disease.

Types of Bias: Biases can arise at any stage of a research study, from the selection of participants to the collection of data and the publication of results. They can lead to inaccurate conclusions, affecting clinical decision-making and healthcare policy. Therefore, recognizing and addressing various types of bias is essential for the integrity of research and the advancement of evidence-based medicine.

Type of BiasDefinitionExample in Primary CarePrevention/Control Strategies
Selection BiasOccurs when individuals selected for a study do not represent the target population.Patients who visit the clinic more frequently are more likely to be included in a study.Use random sampling, ensure representative study populations.
Information BiasArises from systematic errors in data collection.Inaccurate patient self-reporting in surveys or clinical...

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