Cardiomyopathy

ESC working group defines cardiomyopathy as a myocardial disorder in which there is abnormality in the structure and function of the myocytes, in the absence of coronary artery disease , hypertension , valvular heart disease and congenital heart disease that could justify this abnormality

American Heart Association defines cardiomyopathy as a heterogeneous group of diseases of the myocardium associated with mechanical and / or electric dysfunction that usually (but not invariably) exhibit inappropriate ventricular hypertrophy or dilatation due to a variety of etiologies that are frequently genetic

Non-ischaemic disease of the myocardium was conceptualized in 1889 by Fieldler - when he reported a series of fatal cases in young adults with cardiomegaly and heart failure Evans reported unexplained cardiomegaly in families Brigden - was the first to use the term cardiomegaly in 1957 to characterize patients with idiopathic myocardial disease , several among them had familial disease A WHO task force two decades later gave the first classification of cardiomyopathies based on predominant structural and hemodynamic phenotype that is - dilated cardiomyopathy ( DCM )- hypertrophic cardiomyopathy ( HCM ) &- restrictive cardiomyopathy all cardiomyopathies were initially thought to be idiopathic , but discovery in 1990 of a mutation in...