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Cellulitis and erysipelas : antibiotic prescribing guidance summary ( NICE )

This table provides information on the antibiotics used for the treatment of cellulitis and erysipelas as recommended by NICE in adults aged 18 and over, including dosages, course lengths, and the route of administration (oral or IV) where applicable.

This is applicable to adults 18 and over

VariableDescription
First Choice AntibioticFlucloxacillin
Dosage and Course Length500 mg to 1 g four times a day orally for 5 to 7 days or 1 to 2 g four times a day IV
Alternative First Choice Antibiotics for Penicillin Allergy or Unsuitability of FlucloxacillinClarithromycin or Erythromycin (in pregnancy) or Doxycycline
Dosage and Course Length for Clarithromycin500 mg twice a day orally for 5 to 7 days or 500 mg twice a day IV
Dosage and Course Length for Erythromycin (in pregnancy)500 mg four times a day orally for 5 to 7 days
Dosage and Course Length for Doxycycline200 mg on the first day, then 100 mg once a day orally for 5 to 7 days in total
First Choice Antibiotic if Infection Near the Eyes or NoseCo-amoxiclav
Dosage and Course Length for Co-amoxiclav500/125 mg three times a day orally for 7 days or 1.2 g...

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