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Cryptosporidium (Cryptosporidiosis)

Cryptosporidium is a genus of protozoan parasites that poses a significant public health concern due to its ability to cause acute gastroenteritis, particularly in young children and immunocompromised individuals. Globally recognized as the second leading cause of moderate to severe diarrhea in children under two, Cryptosporidium contributes to increased morbidity and mortality rates, especially in developing countries. The organism is notorious for its role in waterborne epidemics, exploiting inadequate water treatment systems to spread.


In humans, Cryptosporidium infection leads to symptoms that mirror choleric infection, including abdominal pain and severe diarrhea. While typically self-limiting in healthy individuals, the infection can be persistent and potentially life-threatening in those with weakened immune systems, such as HIV/AIDS patients, underscoring the need for effective prevention and treatment strategies.


AspectDetails
Host RangeInfects mammals, birds, reptiles, amphibians, fish
Common Species in HumansCryptosporidium hominis (C. hominis), Cryptosporidium parvum (C. parvum)
Infection SitePrimarily the jejunum and ileum; may affect biliary tree, stomach, and lungs in immunocompromised individuals
SymptomsMild to severe watery diarrhea, abdominal pain; fever, nausea, vomiting can occur
Common Age GroupMost commonly seen in children aged 1 to 5 years
Risk GroupsMore severe in individuals with weakened immune systems
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