Diamorphine

Diamorphine, commonly known as heroin, is a powerful opioid analgesic known for its effective pain relief properties. Chemically known as diacetylmorphine or acetomorphine, and also referred to as 3,6-diacetylmorphine, it acts primarily on the central nervous system (CNS) to provide analgesia. While it is a CNS depressant, diamorphine can also induce stimulant actions such as nausea, vomiting, and miosis. Its rapid onset of action and potent analgesic effects make it particularly useful in the management of severe pain associated with surgical procedures, myocardial infarction, terminal illnesses, and for the relief of dyspnoea in acute pulmonary oedema.

Diamorphine has a unique place in medicine and regulatory environments. In the United States, the sale and possession of diamorphine under its street name, heroin, are illegal due to its high potential for abuse and addiction. It is listed as a Schedule I drug under U.S. regulations. However, in the United Kingdom, diamorphine remains a legal prescription drug used under strict controls for its potent analgesic properties, especially in settings requiring rapid and effective pain management. Its use is governed by the fact that it is more soluble and potent than morphine, making it a preferred choice for certain medical conditions, despite its...