Faecal Immunochemical Test ( FIT )

Faecal immunochemical test ( FIT ) test uses antibodies that specifically recognises human haemoglobin

replaced FOB ( Guaiac faecal occult blood test gFOBt ) as primary test for NHS bowel screening program me in 2016 sensitivity to pick up CRC was significantly better in NICE modeling more specific than gFOBt useful in both screening and symptomatic assessment applications greater accuracy in detecting of CRC in symptomatic patients in gHOBt 2 sample from 3 stools were needed whereas FIT requires only 1 stool sample from a single bowel motion( ie easier to use -better uptake ) no dietary interference ie no false positives if patient eats meat whereas in gFOBT false positive results could be seen with upper GI bleeding - this is not the case with FIT FIT can detect cancers at an early stage , particularly adenomas

Refer to secondary care along side +/- FIT aged 40 and over with unexplained weight loss & abdominal pain OR aged 50 and over with unexplained rectal bleeding OR aged 60 and over with IDA ( Iron deficiency anaemia ) or CIBH ( change in bowel habit ) positive faecal occult blood a rectal or abdominal mass aged < 50 with rectal...