Hormone replacement therapy : prescribing guide

This table outlines the primary classes of Hormone Replacement Therapy (HRT) tailored to different stages of menopause. Oestrogen Only HRT is recommended for post-hysterectomy patients, Cyclical or Sequential HRT for those experiencing natural menopause or perimenopause, and Continuous Combined HRT for postmenopausal women. Each class serves distinct clinical needs, optimizing the management of menopausal symptoms and individual patient profiles.

Class	Description
1. Oestrogen Only HRT	Indicated for postmenopausal women who have undergone a hysterectomy, rendering them without a uterus. In such cases, the administration of progesterone is unnecessary due to the absence of endometrial tissue. Therefore, these patients are typically prescribed oestrogen monotherapy as part of their hormone replacement therapy regimen.
2. Cyclical or Sequential HRT	Appropriate for women experiencing a natural menopause or those in the perimenopausal phase, characterized by ongoing menstrual cycles. Cyclical HRT combines oestrogen and progestogen to facilitate regular endometrial shedding and minimize the risk of endometrial hyperplasia or cancer.
3. Continuous Combined HRT	Recommended for postmenopausal women who have not menstruated for at least one year, signifying the onset of full menopause. Continuous combined HRT incorporates hormonal components similar to cyclical HRT but is formulated to suppress menstrual bleeding. Postmenopausal women who have not...

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