Hyperhidrosis – Quick review chart

Hyperhidrosis – excessive sweating

Primary- idiopathic ( no underlying cause ) over-activity of sympathetic nerves in body areas as axilla , palms , soles or craniofacial regions pathology is poorly understood focal primary hyperhidrosis is the most common form axilla is the most common site ( up to 79 % )

b/l and symmetrical peaks 2nd or 3rd decade of life (onset puberty ) duration atleast 6 months ( with no obvious cause ) impairs daily activity happens atleast once / week age of onset < 25 positive family history in 30 % to 50 % no sweating during sleep no change in sweat gland morphology

topical aluminium chloride ( 10-20 % ) chloride hexa hydrate oral ( anti cholinergics as amitriptyline ) , beta blockers , calcium channel blockers , oral propantheline injectibles ( botulinum toxin for axillary HH ) iontophoresis ( small electrical bath ) microwave thermolysis surgical - endoscopic thoracic sympathectomy axillary curettage , liposuction for axillary hyperhidrosis

REFERENCES

Benson R A, Palin R, Holt P J E, Loftus I M. Diagnosis and management of hyperhidrosis BMJ 2013; 347 :f6800 doi:10.1136/bmj.f6800 Diagnosis and management of hyperhidrosis | The BMJ

Lakraj, Amanda-Amrita D et al. “Hyperhidrosis: anatomy, pathophysiology...