Kidney cancer ( Renal cell carcinoma )

RCCs account for 2 % of the global cancer diagnoses and deaths but the incidence has increased In US cancer of the kidney and renal pelvis comprise the 6th most common newly diagnosed cancer in men and 10th most common in women In UK kidney cancer is the 7th most common cancer Globally highest rates are seen in European nations whereas low rates in African and Asian countries Seen more commonly in men ages 50-70 ( NICE 50- 80 ) Men affected more than women in a ratio of 2 : 1 In the US the median age of patients in the SEER database was 64 yrs Most kidney cancers are sporadic but about 4 % of RCCs can be hereditary- if RCC diagnosed at age < 46 possibility of an underlying kidney cancer syndrome should be considered- 10 familial syndromes the confer increased risk of developing RCC- Von Hippel-Lindau disease is the most common form of hereditary RCC Mortality from kidney cancer has decreased as these are often picked up when they have not metastasized due to increased use of abdominal imaging ( for e.g US or CT scan of abdomen or chest ) Screening is not undertaken routinely...