Lichen sclerosus

Lichen Sclerosus (LS) is a chronic, inflammatory skin disorder predominantly affecting the anogenital region. While the exact aetiology remains uncertain, it is generally considered to be an autoimmune condition with possible hormonal and genetic predispositions. LS is known for its characteristic skin changes, which include ivory-coloured, wax-textured spots that may develop into crinkly, thin or hyperkeratotic patches. It presents a unique set of challenges in primary care, ranging from diagnosis to management. This comprehensive quick review tables aims to serve as a quick reference guide for clinicians and medical students to understand the epidemiology, clinical presentation, differential diagnoses, and diagnostic approaches for LS. It is crucial for primary care providers to be familiar with this condition due to its potential for significant morbidity and the risk of malignancy if left untreated.