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Pregnancy : chickenpox exposure

This table provides a concise summary of recommendations for managing exposure to chickenpox or shingles during pregnancy, considering factors that define significant exposure and the use of varicella-zoster immunoglobulin (VZIG) for non-immune pregnant women.

RecommendationDetails
Exposure Assessment- Assess contact significance based on infection type, timing, and duration of contact.
- Consider: - Type: Chickenpox, disseminated zoster, immunocompetent individuals with exposed lesions, or immunocompromised individuals with localized zoster.
- Timing: Specific timeframes for exposure significance.
- Closeness: Maternal/neonatal, continuous home, 15+ minutes in the same room, face-to-face.
Immune Status and Reassurance- If the woman has a definite history of chickenpox, shingles, or two doses of a varicella-containing vaccine, and is not immunocompromised, reassure her that she is not at risk of chickenpox because immunity can be assumed.
Testing for VZV Immunity- Test pregnant women with uncertain chickenpox history, especially from tropical areas, for varicella-zoster virus (VZV) immunity.
- If results can be obtained within 24–48 hours of initial exposure, testing in primary care may be appropriate.
VZIG Administration for Non-Immune- Offer varicella-zoster immunoglobulin (VZIG) to non-immune pregnant women with significant contact as soon as possible (within 10 days of rash appearance in the index case)
-...

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