Prostate Cancer : Hormone therapy managing adverse effects

Hormone therapy, also known as androgen deprivation therapy (ADT), is a cornerstone in the treatment of prostate cancer. It works by reducing the levels of male hormones, or androgens, such as testosterone, which can fuel the growth of prostate cancer cells. Hormone therapy is used in various settings – it may be given to men with advanced or metastatic cancer, as well as those with earlier stages of prostate cancer in combination with other treatments like radiation therapy.

The goal of hormone therapy in prostate cancer is to slow down or halt the growth of cancer cells. However, this treatment does not cure prostate cancer and is often used to control the disease for as long as possible. Intermittent hormone therapy for prostate cancer involves alternating periods of treatment with breaks. The rationale behind this approach is to potentially reduce the side effects associated with continuous treatment, thereby improving the patient's quality of life.

Managing the adverse effects of hormone therapy in prostate cancer requires a multifaceted approach. This includes pharmacological interventions, such as medroxyprogesterone and cyproterone acetate for hot flushes, and PDE5 inhibitors for sexual dysfunction. Additionally, lifestyle modifications and supportive therapies like exercise programs and psychosexual counseling play...