Prostate cancer

Malignant neoplasm of the prostate gland ( PCa is a widely used acronym to denote prostate cancer )

How common- Second most prevalent cancer in men worldwide ( Lung cancer is first ) Happens more in developed countries - incidence of PCa is less in Asian countries compared to Western nations In 2014 there were 46000 new diagnosis of PCa - this accounts for 13 % of all new cancers diagnosed ( NICE 2019 ) 1 in 8 men will get prostate cancer at some point in life More than 1/2 the cases of PCa in UK each year are in men aged 70 ( 2012 ) and over - incidence is highest in men aged 90 and over Mortality rate has been falling worldwide Inversely associated with deprivation with higher incidence in affluent areas in the UK

Risk factors-Age - affects predominantly older men Black ethnicity Family history Obesity High levels of dietary fat

Anatomy-The gland is about 3 cm long , about the size of a walnut and weighs approximately 20 gms About 2/3 rd is glandular and remaining 1/3rd is fibromuscular- cancer normally begins with a mutation in normal prostate glandular cells -usually starting with the peripheral...