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Randomized Controlled Trials (RCTs)

Randomized Controlled Trials (RCTs)

Randomized Controlled Trials (RCTs) are considered the gold standard in clinical research for evaluating the effectiveness of new treatments or interventions. They are prospective studies that randomly allocate participants to either an intervention group or a control group. The intervention group receives the new or experimental treatment, while the control group receives the standard of care or a placebo. They provide the most reliable evidence on the efficacy of interventions because of their unique design, which minimizes bias and maximizes the reliability of results. RCTs are crucial in evidence-based medicine, guiding clinical decision-making and policy.


Let us review some key terms to understand when studying about RCT's


TermDefinitionImportance in RCTs
Randomized Controlled Trial (RCT)A study design where participants are randomly assigned to either the treatment or control group.Ensures the comparability of groups and minimizes bias.
RandomizationThe process of assigning study participants to treatment or control groups by chance.Reduces selection bias and confounding, ensuring each participant has an equal chance of being assigned to any group.
Control GroupThe group in an RCT that receives a placebo, no intervention, or standard treatment for comparison.Serves as a baseline to measure the effect of the treatment....

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