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Atherosclerosis affecting the coronary arteries -Coronary artery disease ( CAD ) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries , whether obstructive or non-obstructive (European Society of Cardiology 2019 )
Angina- most common symptom of Ischaemic heart disease
.Also known as typical angina- it is the occurrence of symptoms on exertion and alleviated at rest or with use of nitroglycerin
Unstable angina -Myocardial ischaemia at rest or on minimal exertion in the absence of acute myocardial necrosis ( part of ACS ) most common cause is a narrowing of the coronary artery as a result of a thrombus that develops on a disrupted atherosclerotic plaque and is nonocclusive other causes can include Prinzmetal angina-rare ( vasospasm of coronary artery ) the pain would be experienced at rest rather than on exertion.
Major risk factors for atherosclerotic heart disease diabetes smoking tobbacco hypertension lipid disorders Obesity genetic factors ( a family h/o IHD )
Causes of angina include imbalance between myocardial oxygen demand and supply coronary vasospasm aortic valve disease microvascular coronary dysfunction oesophageal spasm and reflux anaemia .
How common -Worldwide ischaemic heart disease is the leading cause of death and lost life years in...
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