Staphylococcal Scalded Skin Syndrome (SSSS) : Overview

For clinicians working in primary care settings, it is essential to have a succinct yet comprehensive understanding of various medical conditions for effective diagnosis and treatment. The following table provides an overview of Staphylococcal Scalded Skin Syndrome (SSSS), a condition that primarily affects neonates and young children but can also occur in adults. The table covers key aspects ranging from introduction, aetiology, and epidemiology to differential diagnosis and prognosis. This summary aims to serve as a quick reference guide to equip healthcare professionals with the essential information they need for the management of SSSS.

Section	Information
Introduction	Also known as Ritter disease. Characterized by skin denudation caused by exotoxin-producing strains of Staphylococcus species. Typically presents 48 hours after birth; rare in children older than six years; may affect immunocompromised adults and those with severe renal disease.
Aetiology	Caused by epidermolytic exotoxins produced by some strains of Staphylococcus. Usually follows localized infections like those of the upper respiratory tract, ears, conjunctiva, or umbilical stump. In adults, could be due to abscess, arteriovenous fistula infection, or septic arthritis. Source often not identifiable.
Epidemiology	Incidence in the general population estimated between 0.09-0.56 cases per one million people Incidence in children less than one...

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