Syringe Driver : Medication compatibility guide

Syringe drivers are crucial tools in administering continuous medication, especially in palliative care settings, ensuring patient comfort and symptom management. Here's an introduction and simplification of the main messages regarding the preparation and use of syringe drivers:

Introduction: Syringe drivers allow for the precise delivery of medications over a set period, typically 24 hours. They are particularly valuable in managing symptoms such as pain, nausea, and secretions in patients who may not be able to take oral medications. The proper setup and use of syringe drivers are essential to ensure both the effectiveness of the medication and the safety of the patient.

Main Messages:

1. Preparation Time: Always prepare syringe drivers immediately before use to ensure medication potency and integrity, utilizing strict aseptic technique.

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3. Diluent Choice: Water for Injection (WFI) is the preferred diluent. Use 0.9% saline only when necessary, as it's not compatible with certain medications like cyclizine, diamorphine, or haloperidol.

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5. Compatibility and Stability: Before administration, check the physical compatibility of drug combinations (e.g., no discolouration, clouding, or crystallization) and observe for any changes per trust guidelines.

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7. Volume Calculation: Determine the total volume needed for the drugs. Mix them in the smallest feasible volume to minimize incompatibility risks and adverse...