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Cutaneous lupus (CLE) showcases in acute, subacute, and chronic forms. Commonly, SLE starts with acute CLE. Half of those with subacute CLE will have mild SLE symptoms, while chronic CLE is mostly a skin-only issue, affecting just 5% of SLE patients. Acute CLE is characterized by a central face "butterfly" rash, potential blisters, a rash resembling drug reactions, mucosal sores, sun-sensitivity, and hair loss. On the other hand, subacute CLE features psoriasis-like patches, overlapping circular lesions, minimal scarring, and is sun-sensitive, primarily affecting the trunk and arms
| Aspect | Details |
|---|---|
| Definition | SLE is an autoimmune disorder where the immune system mistakenly targets its own tissues. |
| Nature of Disease | It exhibits diverse characteristics, with varying auto-antibody production patterns and multiple organ impacts. |
| Severity Range | From mild issues like skin rashes to severe, life-threatening problems affecting vital organs. |
| Clinical Variability | Its clinical signs can be diverse, often overlapping with other conditions. |
| Skin Involvement Frequency | Skin problems arise in approximately 80% of SLE patients, with a quarter showing skin symptoms as their first SLE sign. |
| Cutaneous Features | - LE-specific lesions: These often result from or worsen with sun exposure, typically appearing on sun-exposed regions like the face, neck, and upper back. |
| - LE-nonspecific... |
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