Testosterone deficiency syndrome

Testosterone deficiency ( Hypogonadism ) in adult men is defined by low testosterone levels with associated variable symptoms suggestive of androgen deficiency ( Hypogonadism is when testes is unable to fulfill one or both of its major functions ie testosterone and sperm production )

primary male hormone ( Testosterone - TT ) plays an important role in the physiology of organs which have androgen receptors as skin , muscle , liver , bone , bone marrow , brain , sexual organs modulating male sexual development , adult male reproductive health and sexual function maintaining lean muscle mass , bone mineral density and fat metabolism testes main function - testosterone and sperm production testes - responsible for > 90 % of testosterone production diurnal variation in T levels due to pulsatile release of gonadotrophins by HPG - peak levels are seen in morning hours

incidence of testosterone deficiency ( TD ) increases with age testosterone production declines after age 30 ( on an average by 100 ng / dL every 10 yrs on an average 1-2 % per yr ) hypogonadism affects up to 40 % of men > 45 -only about 5 % are diagnosed and treated reported prevalence up...