Thrombophilia testing : NICE guidance

The table below provides a clear and concise representation of the thrombophilia testing guidelines as recommended by NICE in the guideline: Venous thromboembolic disease: diagnosis management and thrombophilia testing

Guideline	Explanation
Do not offer testing for hereditary thrombophilia to people who are continuing anticoagulation treatment.	People on continuous anticoagulation treatment shouldn't be tested for hereditary thrombophilia because the treatment might impact the accuracy of the results.
Do not offer thrombophilia testing to people who have had provoked DVT or PE.	If the DVT (Deep Vein Thrombosis) or PE (Pulmonary Embolism) has a known cause (provoked), there's no need to test for thrombophilia since the cause is identified.
Consider testing for antiphospholipid antibodies in people who had unprovoked DVT or PE if it's planned to stop anticoagulation treatment.	For those with unexplained DVT or PE, antiphospholipid antibody testing may be considered, especially if discontinuing anticoagulation treatment. However, the test's accuracy can be influenced by anticoagulants, so specialist advice might be needed.
Consider testing for hereditary thrombophilia in people who had unprovoked DVT or PE and who have a first‑degree relative with DVT or PE history if planning to stop anticoagulation treatment.	Individuals with unexplained DVT or PE and a family history...

Try our Free Plan to get the full article.