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Advice about diet - diet lifestyle adherence to drug treatment
Indivdualised hba1c target- Preferences Co-morbidities Risks from polypharmacy and tight control Ability to achieve longer term risk reduction benefits Measure Hba1c 3-6 monthly as appropriate If Hba1c lower than target and no hypoglycaemia --> encourage to maintain it
Choose drugs based on- Effectiveness Safety Tolerability Individual clinical circumstances Preferences and needs Licensing and cost
Self- monitoring of blood glucose -Do not routinely offer self monitoring unlessâ—‹ on insulinâ—‹ on oral medication that may increase their risk of hypoglycaemia while driving or operating machineryâ—‹ pregnant or planning to become pregnantâ—‹ evidence of hypoglycaemic episodes
Adults who can take metformin .Hba1c rises to 48 mmol.mol ( 6.5 % ) on lifestyle interventions.Try modified-release metformin if standard metformin not tolerated
Hba1c rises to 58 ( 7.5 % ) →First intensification-Consider dual therapy○ Metformin + DPP4inhibitor○ Metformin + Pioglitazone○ Metformin + Sulphonylurea○ Metformin + SGLT- 2 inhibitor * SGLT-2i * - dapagliflazocin ,canagliflazocin and empagliflazocin are recommended as options in dual Rx with metformin under certain conditions , as options in triple Rx and in combination with insulin. They can also be used as monotherapy in adults who cannot take or tolerate metformin. Warn...
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