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UTIs are one of the most common bacterial infections of childhood In ambulatory care about 6 % of all acutely ill children have UTI's Data has shown that about 8 % of all girls and 2 % of all boys will have atleast one episode by 7 yrs of age and about 12 % to 30 % of those will experience a recurrence Short female urethra and male circumcision account for marked female preponderance beyond infancy Bimodal peaks are seen with the first one in infancy and other peak from 2-4 yrs
Most common causes for UTI are bacteriaâ—‹ viruses , fungi and parasites can occasionally also be responsibleâ—‹ Adenoviruses can be associated with haemorrhagic cystitisâ—‹ Candida can cause UTIs in immunocompromised children Escherichia coli ( E.coli ) is the most common uropathogen accounting for about 80 % to 90 % of paediatric UTI's Other members of the Enterobacteriaceae family - Klebsiella , Proteus , Citrobacter , Serratia and Enterobacter can also be responsible Pathogenesis of UTI is complex -several host and pathogen factors influence the course of the illness and its outcome E Coli- Special properties as fimbriae which attach to the uroepithelial cell surface allows them to overcome...
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