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Sepsis : Introduction to NICE Guidelines on Sepsis ( Recognition, Diagnosis, and Early Management )

Sepsis remains a critical medical emergency, and timely recognition is essential to improving outcomes. The NICE guideline NG51, initially published on 13 July 2016 and last updated on 19 March 2024, offers comprehensive recommendations on the recognition, diagnosis, and early management of suspected sepsis.


The recent update of the NICE guideline NG51 on suspected sepsis, published on March 19, 2024, emphasizes the critical importance of early recognition, diagnosis, and management of sepsis in primary care settings. This guideline revision reflects a growing body of evidence underscoring the necessity for timely intervention in sepsis cases, which is pivotal for improving patient outcomes. The updated guidelines aim to enhance the awareness and application of sepsis protocols among primary care clinicians, thereby facilitating better management of this life-threatening condition.


One of the key changes in the updated NICE guidelines is the emphasis on the use of structured screening tools to enhance the early identification of sepsis. The incorporation of standardized assessment protocols, such as the Modified Early Warning Score (MEWS), is designed to streamline the recognition process and ensure that clinicians can promptly initiate the necessary interventions (Roney et al., 2019). This aligns with findings from various studies indicating...

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